DHEA

1. What it 7-Keto™ DHEA ?

7-Keto, as a downstream metabolite of DHEA, is produced in the body during the degradation of DHEA. It is structurally practically identical to DHEA.
7- Keto™ DHEA was discovered by Dr. Henry Lardy from the Institute of Research on Enzymes at the University of Wisconsin in Madison, who spent the last 10 years examining over 150 metabolites. 7- Keto™ DHEA has many benefits including strengthening immune systems, enhancing memory, contributing to the treatment of Alzheimer's disease and favouring weight loss.


2. 7-Keto™ DHEA is much safer than DHEA ?

The main concern about DHEA is that part of it is converted into sex hormones such as testosterone and estrogens. People with a personal or a family history of hormonal-dependent cancer risk (prostate, breast, ovarian) worry about the intake of DHEA.

Some people do not support the side effects that brings an increase of sex hormones (growth of body hair, beard, ears, nostrils, acne).For these people, 7-Keto™ DHEA is an ideal alternative. Up to 2000 mg/kg of 7-Keto™ DHEA have been administered to rats and 500 mg /kg to primates without side effects*1. It should be noted that 500 mg /kg is 3.5 grams in a normal 70 kg human, human being recommended intake is much less lower than the rats and primates dosage so it could be taken safely. One toxicological study revealed that an intake of up to 2g/kg of 7-Keto™ DHEA taken *2.

*1 Source :Zenk, J. Living Longer in the Boomer Age. NY: Advanced Research Press, 1998.

*2 Source: Biochem Biophys Res Commun. 1999 Jan 8;254(1):120-3. An acute oral gavage study of 3beta-acetoxyandrost- 5-ene-7,17-dione (7-oxo-DHEA-acetate) in rats. Lardy H, Henwood SM, Weeks CE.


3. It is also more powerful that DHEA ?

7-Keto™ DHEA not only produces the same positive effects as DHEA, buy it also does it more effectively. Dr. Henry Lardy researches showed that 7-Keto™ DHEA is 2,5 times more powerful than DHEA.

Laboratory tests on mice demonstrate 7-Keto DHEA protects against memory loss*3
- 7-Keto™ DHEA boosts the immune system because it increases the production Interleukin-2 and specialized white blood cells that strengthen immune defenses*3
- 7-Keto™ DHEA reduces cardiovascular risks as it reduces your risk of heart disease, heart attack and stroke*3
- 7-Keto™ DHEA favors fat burning as it increase the rate of thermogensis*3
- 7-Keto™ DHEA allow diabetes prevention*3
- 7-Keto™ DHEA increases energy*3

*3 Source:: Health Sciences Institute, Members Alert, Oct. 1999, pp. 1, 3-6.


4. A new hope for the overweight ?

7-Keto™ DHEA promotes weight loss as it increases your body’s basic rate of metabolism. This is due to the increase of the liver production of thermogenetic enzymes and the production of the thyroid hormone T3 (without any effects on TSH or T4 and thyroid function).

7-Keto™ DHEA may help lower the body's weight set point, providing a way to achieve greater weight loss.

7- Keto™ DHEA’s ability to promote weight loss in overweight people has been investigated in one double-blind trial*4. During this study, the participants followed a 1,800-calorie-per-day diet and exercised three times per week for 45 minutes. Each subject was given either a placebo or 100 mg of 7-KETO DHEA twice daily. After eight weeks, the persons supplemented in 7-KETO DHEA had lost more weight and lowered their percentage of body fat further compared to those taking a placebo.

*4 Source: Colker CM, Torina GC, Swain MA, Kalman DS. Double-blind study evaluating the effects of exercise plus 3-acetyl-7-oxo-dehydroepiandrosterone on body composition and the endocrine system in overweight adults. J Exercise Physiology Online 1999;2(4).


5. Who should take 7-Keto™ DHEA ?

7-Keto™ DHEA can be taken by all the persons taking DHEA who are willing to pay a little bit more for a safer and more efficient supplement. When the intake of DHEA is not possible 7-Keto™ DHEA can be taken.7-Keto™ DHEA is an alternative for the persons who cannot take DHEA because of the risk of hormonal-dependent cancer. Persons willing to control their weight definitively should consider a supplementation of 7-Keto™ DHEA. For some men the intake of DHEA excessively aromatize testosterone, the intake of 7-Keto™ DHEA will avoid this.


6. What is the recommended dose ?

Persons willing to go for an anti-aging programme should take twenty-five to 50mg per day. If you take 50 mg per day it is recommended to divide the intake between two meals. Higher doses can be advised for limited periods.